IDH-C227

Modify Date: 2024-01-11 19:37:40

IDH-C227 structure	Common Name	IDH-C227
	CAS Number	1355324-14-9	Molecular Weight	498.59100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₃₁FN₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of IDH-C227

IDH-C227 is a potent and selective IDH1R132H inhibitor. IDH-C227 has anticancer effcts[1].

Name	2-((4-cyanophenyl)amino)-N-(2-(cyclohexylamino)-2-oxo-1-(o-tolyl)ethyl)-N-(3-fluorophenyl)acetamide

Description	IDH-C227 is a potent and selective IDH1R132H inhibitor. IDH-C227 has anticancer effcts[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Isocitrate Dehydrogenase (IDH)
In Vitro	IDH-C227 shows anticancer effcts, with IC50 values of <0.1 μM and 0.25 μM against HT1080 and U87MG cells, respectively[1].
References	[1]. Hanumantha Rao Madala, et al. Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML: Current and Future Therapeutic Strategies. Cancers (Basel). 2018 Feb 11;10(2):49.

Molecular Formula	C₃₀H₃₁FN₄O₂
Molecular Weight	498.59100
Exact Mass	498.24300
PSA	85.23000
LogP	6.10498

DC Chemicals Limited
China
Product Name: IDH-C227
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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