Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Boc-5-aminopentanoic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
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Email: enquiry@dycnchem.com

27219-07-4

27219-07-4 structure

Name: Boc-NH-C4-acid
Chemical Name: 5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid
CAS Number: 27219-07-4
Molecular Formula: C₁₀H₁₉NO₄
Molecular Weight: 217.262
Catalog: Biochemical Amino acids and their derivatives BOC-amino acid
Create Date: 2018-07-05 14:31:34
Modify Date: 2026-07-16 22:13:05
Boc-NH-C4-acid is a PROTAC linker, which belongs to a Alkyl/ether linker. Boc-NH-C4-acid can be used in the synthesis of the compound PROTAC1, and specifically degrades EED, EZH2, and SUZ12 in the PRC2 Complex.

Name	5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid
Synonyms	5-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)pentanoic acid N-T-BUTOXYCBONYL-5-AMINOPENTANOIC ACID MFCD00076903 5-[(tert-Butoxycarbonyl)amino]valeric Acid BOC-NH-(CH2)4-COOH Boc-5-Ava-OH 5-(tert-Butoxycbonylamino)pentanoic Acid N-Boc-5-aminovaleric Acid N-Boc-5-aminopentanoic Acid N-(tert-Butoxycarbonyl)-5-aminovaleric Acid Boc-2-amino-5-phenylpentanoic acid DCHA 5-(TERT-BUTOXYCBONYLAMINO)VALERIC ACID Hexanedioic acid, 2-amino-, 1-(1,1-dimethylethyl) ester N-(tert-Butoxycbonyl)-5-aminovaleric Acid > N-(tert-Butoxycbonyl)-5-aMinovaleric Acid BOC-5-AMINOVALERIC ACID RECHEM EM WB 0073 BOC-5-AMINOPENTANOIC ACID Boc-5-aminovaleric acid (HPLC) 5-(tert-Butoxycarbonylamino)pentanoic Acid N-Boc-5-aminovaleric Acid PROTAC Linkers,Inhibitor,protac,Boc NH C4 acid,inhibit,BocNHC4acid,Boc-NH-C-4-acid,linker 5-Boc-amino-pentanoic acid 5-(tert-Butoxycarbonylamino)valeric Acid N-BOC-5-AMINOVALERIC ACID N-(tert-Butoxycbonyl)-5-aminopentanoic Acid 5-(N-t-butoxycarbonylamino)valeric acid 5-[(2-methylpropan-2-yl)oxycbonylamino]pentanoic acid Boc-d-aMinovaleric acid PENTANOIC ACID, 5-[[(1,1-DIMETHYLETHOXY)carbonyl]AMINO] 5-(BOC-AMINO)PENTANOIC ACID 5-(N-t-butyloxycarbonylamino)-pentanoic acid (Tert-Butoxy)carbonyl 5-Ava-OH 5-[(2-methylpropan-2-yl)oxycbonylamino]pentanoicaci Boc-5-aminopentanoic acid 5-(TERT-BUTOXYCBONYLAMINO)PENTANOIC ACID N-BOC-5-AMINOPENTANOIC ACID 5-[(tert-Butoxycarbonyl)amino]pentanoic acid 5-(N-t-butoxycarbonylamino)pentanoic acid 5-(BOC-AMINO)VALERIC ACID 5-[(tert-Butyloxycbonyl)amino]pentanoic acid 5-[[(1,1-Dimethylethoxy)carbonyl]amino]-pentanoic acid 5-(Boc-amino)pentanoic acid, 5-(Boc-amino)valeric acid 5-[[(1,1-Dimethylethoxy)carbonyl]amino]pentanoic acid BOC-DELTA-AMINOVALERIC ACID Boc-5-AMinovaleric acid Boc-5-AMinovaleric acid 5-(Boc-amino)valeric acid N-(tert-Butoxycbonyl)-5-aminop 5-(N-BOC-Amino)pentanoic acid 2-Methyl-2-propanyl 6-hydroxy-6-oxonorleucinate 5-[[(1,1-Dimethylethyl)oxy]carbonyl]aminopentanoic acid BOC-APE(5)-OH 5-(Boc-amino)pentanoic Acid N-DELTA-T-BUTOXYCBONYL-DELTA-AMINOVALERIC ACID 5-(N-Boc-amino)valeric acid Boc-5-aminopentanoic acid //BP tert-butyl 1-phenyl-2,9,12,15-tetraoxahtadecan-17-oate N-Boc-5-aminopentanoic Acid boc-5-aminovaleric acid BOC-5-AVA-OH 5-(N-tert-butoxycarbonylamino)-pentanoic acid 5-(Boc-amino)valeric AcidN-Boc-5-aminovaleric Acid N-(tert-Butoxycarbonyl)-5-aminopentanoic Acid

Description	Boc-NH-C4-acid is a PROTAC linker, which belongs to a Alkyl/ether linker. Boc-NH-C4-acid can be used in the synthesis of the compound PROTAC1, and specifically degrades EED, EZH2, and SUZ12 in the PRC2 Complex.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
References	[1]. [1].Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9.

Density	1.1±0.1 g/cm3
Boiling Point	331.7±27.0 °C at 760 mmHg
Melting Point	48-52 °C(lit.)
Molecular Formula	C₁₀H₁₉NO₄
Molecular Weight	217.262
Flash Point	154.4±23.7 °C
Exact Mass	217.131409
PSA	75.63000
LogP	0.84
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.475
Storage condition	2-8°C

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2924199090

24424-99-5

660-88-8

~95%

27219-07-4

Literature: Gavande, Navnath; Kim, Hye-Lim; Doddareddy, Munikumar R.; Johnston, Graham A. R.; Chebib, Mary; Hanrahan, Jane R. ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 4 p. 402 - 407

74651-77-7

660-88-8

~47%

27219-07-4

Literature: Lippard, Stephen J.; Barnes, Carmen M.; Haskel, Ariel; Barnes, Katie R. Patent: US2004/235712 A1, 2004 ; Location in patent: Page/Page column 34 ;

85908-96-9

~90%

27219-07-4

Literature: Flynn, Daniel L.; Zelle, Robert E.; Grieco, Paul A. Journal of Organic Chemistry, 1983 , vol. 48, # 14 p. 2424 - 2426

34619-03-9

660-88-8

~75%

27219-07-4

Literature: Hartlieb, Matthias; Pretzel, David; Kempe, Kristian; Fritzsche, Carolin; Paulus, Renzo M.; Gottschaldt, Michael; Schubert, Ulrich S. Soft Matter, 2013 , vol. 9, # 18 p. 4693 - 4704

41840-28-2

660-88-8

~94%

27219-07-4

Literature: Ishida, Hideharu; Ogawa, Yuji; Imai, Yasuyuki; Kiso, Makoto; Hasegawa, Akira; et al. Carbohydrate Research, 1989 , vol. 194, p. 199 - 208

24424-99-5

497-19-8

660-88-8

27219-07-4

Literature: Nisshin Flour Milling Co., Ltd. Patent: US6252041 B1, 2001 ;

675-20-7

27219-07-4

Literature: Flynn, Daniel L.; Zelle, Robert E.; Grieco, Paul A. Journal of Organic Chemistry, 1983 , vol. 48, # 14 p. 2424 - 2426

24424-99-5

27219-07-4

Literature: Flynn, Daniel L.; Zelle, Robert E.; Grieco, Paul A. Journal of Organic Chemistry, 1983 , vol. 48, # 14 p. 2424 - 2426

Precursor 8
24424-99-5 660-88-8 74651-77-7 85908-96-9
34619-03-9 41840-28-2 497-19-8 675-20-7
DownStream 8
51644-96-3 83948-54-3 660-88-8 75178-90-4
2446-62-0 88313-82-0 91419-47-5 60811-47-4

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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