Boc-NH-C4-acid structure
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Common Name | Boc-NH-C4-acid | ||
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CAS Number | 27219-07-4 | Molecular Weight | 217.262 | |
Density | 1.1±0.1 g/cm3 | Boiling Point | 331.7±27.0 °C at 760 mmHg | |
Molecular Formula | C10H19NO4 | Melting Point | 48-52 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 154.4±23.7 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of Boc-NH-C4-acidBoc-NH-C4-acid is a PROTAC linker, which belongs to a Alkyl/ether linker. Boc-NH-C4-acid can be used in the synthesis of the compound PROTAC1, and specifically degrades EED, EZH2, and SUZ12 in the PRC2 Complex. |
Name | 5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid |
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Synonym | More Synonyms |
Description | Boc-NH-C4-acid is a PROTAC linker, which belongs to a Alkyl/ether linker. Boc-NH-C4-acid can be used in the synthesis of the compound PROTAC1, and specifically degrades EED, EZH2, and SUZ12 in the PRC2 Complex. |
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Related Catalog | |
Target |
Alkyl/ether |
References |
Density | 1.1±0.1 g/cm3 |
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Boiling Point | 331.7±27.0 °C at 760 mmHg |
Melting Point | 48-52 °C(lit.) |
Molecular Formula | C10H19NO4 |
Molecular Weight | 217.262 |
Flash Point | 154.4±23.7 °C |
Exact Mass | 217.131409 |
PSA | 75.63000 |
LogP | 0.84 |
Vapour Pressure | 0.0±1.5 mmHg at 25°C |
Index of Refraction | 1.475 |
Storage condition | 2-8°C |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi: Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2924199090 |
~95% Boc-NH-C4-acid CAS#:27219-07-4 |
Literature: Gavande, Navnath; Kim, Hye-Lim; Doddareddy, Munikumar R.; Johnston, Graham A. R.; Chebib, Mary; Hanrahan, Jane R. ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 4 p. 402 - 407 |
~47% Boc-NH-C4-acid CAS#:27219-07-4 |
Literature: Lippard, Stephen J.; Barnes, Carmen M.; Haskel, Ariel; Barnes, Katie R. Patent: US2004/235712 A1, 2004 ; Location in patent: Page/Page column 34 ; |
~90% Boc-NH-C4-acid CAS#:27219-07-4 |
Literature: Flynn, Daniel L.; Zelle, Robert E.; Grieco, Paul A. Journal of Organic Chemistry, 1983 , vol. 48, # 14 p. 2424 - 2426 |
~75% Boc-NH-C4-acid CAS#:27219-07-4 |
Literature: Hartlieb, Matthias; Pretzel, David; Kempe, Kristian; Fritzsche, Carolin; Paulus, Renzo M.; Gottschaldt, Michael; Schubert, Ulrich S. Soft Matter, 2013 , vol. 9, # 18 p. 4693 - 4704 |
~94% Boc-NH-C4-acid CAS#:27219-07-4 |
Literature: Ishida, Hideharu; Ogawa, Yuji; Imai, Yasuyuki; Kiso, Makoto; Hasegawa, Akira; et al. Carbohydrate Research, 1989 , vol. 194, p. 199 - 208 |
~% Boc-NH-C4-acid CAS#:27219-07-4 |
Literature: Nisshin Flour Milling Co., Ltd. Patent: US6252041 B1, 2001 ; |
~% Boc-NH-C4-acid CAS#:27219-07-4 |
Literature: Flynn, Daniel L.; Zelle, Robert E.; Grieco, Paul A. Journal of Organic Chemistry, 1983 , vol. 48, # 14 p. 2424 - 2426 |
~% Boc-NH-C4-acid CAS#:27219-07-4 |
Literature: Flynn, Daniel L.; Zelle, Robert E.; Grieco, Paul A. Journal of Organic Chemistry, 1983 , vol. 48, # 14 p. 2424 - 2426 |
Precursor 8 | |
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DownStream 8 | |
HS Code | 2924199090 |
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Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
5-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)pentanoic acid |
5-[(tert-Butoxycarbonyl)amino]pentanoic acid |
5-(N-t-butoxycarbonylamino)pentanoic acid |
5-[[(1,1-Dimethylethoxy)carbonyl]amino]-pentanoic acid |
MFCD00076903 |
5-[(tert-Butoxycarbonyl)amino]valeric Acid |
5-(Boc-amino)valeric acid |
Boc-5-Ava-OH |
N-(tert-Butoxycarbonyl)-5-aminovaleric Acid |
2-Methyl-2-propanyl 6-hydroxy-6-oxonorleucinate |
Hexanedioic acid, 2-amino-, 1-(1,1-dimethylethyl) ester |
5-(Boc-amino)pentanoic Acid |
5-(tert-Butoxycarbonylamino)pentanoic Acid |
5-(N-Boc-amino)valeric acid |
N-Boc-5-aminovaleric Acid |
5-Boc-amino-pentanoic acid |
5-(tert-Butoxycarbonylamino)valeric Acid |
N-Boc-5-aminopentanoic Acid |
5-(N-t-butoxycarbonylamino)valeric acid |
Pentanoic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]- |
boc-5-aminovaleric acid |
5-(N-tert-butoxycarbonylamino)-pentanoic acid |
5-(N-t-butyloxycarbonylamino)-pentanoic acid |
N-(tert-Butoxycarbonyl)-5-aminopentanoic Acid |
Boc-5-aminopentanoic acid |