6991-10-2

6991-10-2 structure

Name: Swertisin
Chemical Name: apigenin 6-glucosyl-7-o-methyl ether
CAS Number: 6991-10-2
Molecular Formula: C₂₂H₂₂O₁₁
Molecular Weight: 462.404
Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
Create Date: 2018-09-24 08:56:28
Modify Date: 2024-01-11 18:22:44
Swertisin, a C-glucosylflavone isolated from Swertia japonica, is known to have antidiabetic, anti-inflammatory and antioxidant effects. Swertisin is an adenosine A1 receptor antagonist[1][2].

Name	apigenin 6-glucosyl-7-o-methyl ether
Synonyms	SWERTISIN SWERTISIN(P) 4H-1-Benzopyran-4-one, 6-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy- Sorbifolin 6-O-β-glucopyranoside apigenin-7-methylether-6-C-glucoside 6-C-glucopyranosyl-7-O-methylapigenin 7-O-methylapigenin mono-6-C-glucoside 5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4-oxo-4H-chromen-6-yl β-D-glucopyranoside

Description	Swertisin, a C-glucosylflavone isolated from Swertia japonica, is known to have antidiabetic, anti-inflammatory and antioxidant effects. Swertisin is an adenosine A1 receptor antagonist[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
References	[1]. Oh HK, et al. Swertisin ameliorates pre-pulse inhibition deficits and cognitive impairment induced by MK-801 in mice. J Psychopharmacol. 2017 Feb;31(2):250-259. [2]. Lee HE, et al. Swertisin, a C-glucosylflavone, ameliorates scopolamine-induced memory impairment in mice with its adenosine A1 receptor antagonistic property. Behav Brain Res. 2016 Jun 1;306:137-45.

16049-42-6

~38%

6991-10-2

1343403-87-1

50-99-7

121-34-6

6991-10-2

Literature: Wu, Yi; He, Feng; Pan, Qin; Shi, Yao; Min, Zhida; Liang, Jingyu Chemistry of Natural Compounds, 2011 , vol. 47, # 3 p. 369 - 372

6980-40-1

6991-10-2

Literature: Fujita; Inoue Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 7 p. 2342 - 2348

Precursor 2
16049-42-6 6980-40-1
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