Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: carbamazepine-10,11-epoxide
Price: ￥1906.0/100mg ￥516.0/5mg ￥596.0/25mg
Purity: 97.0%
Stocking Period: 1 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Carbamazepine 10,11-epoxide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

36507-30-9

36507-30-9 structure

Name: carbamazepine-10,11-epoxide
Chemical Name: carbamazepine-10,11-epoxide
CAS Number: 36507-30-9
Molecular Formula: C₁₅H₁₂N₂O₂
Molecular Weight: 252.26800
Catalog: analytical chemistry Standard Forensic and veterinary standards
Create Date: 2018-03-04 08:00:00
Modify Date: 2024-01-02 21:25:05
Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures[1].

Name	carbamazepine-10,11-epoxide
Synonyms	1a,10b-Dihydro-6H-dibenzo(b,f)oxireno[d]azepine-6-carboxamide Carbamazepine 10,11-Epoxide Carbamazepine epoxide Carbamazepine-10,11-epoxide Carbamazepine10,11-Epoxide 6H-Dibenz[b,f]oxireno[d]azepine-6-carboxamide,1a,10b-dihydro-

Description	Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures[1].
Related Catalog	Research Areas >> Neurological Disease

Density	1.377g/cm3
Boiling Point	390.2ºC at 760mmHg
Melting Point	204-206ºC
Molecular Formula	C₁₅H₁₂N₂O₂
Molecular Weight	252.26800
Flash Point	189.8ºC
Exact Mass	252.09000
PSA	58.86000
LogP	3.79470
Index of Refraction	1.686
Storage condition	−20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HQ4430000

CHEMICAL NAME :: 6H-Dibenz(b,f)oxiren(d)azepine-6-carboxamide, 1a,10b-dihydro-

CAS REGISTRY NUMBER :: 36507-30-9

LAST UPDATED :: 199706

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C15-H12-N2-O2

MOLECULAR WEIGHT :: 252.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 420 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TAKHAA Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970- Volume(issue)/page/year: 37,12,1978 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 9600 mg/kg

SEX/DURATION :: female 2 week(s) pre-mating female 1-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 279,1237,1996

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 19200 mg/kg

SEX/DURATION :: female 2 week(s) pre-mating female 1-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 279,1237,1996

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 32 gm/kg

SEX/DURATION :: female 2 week(s) pre-mating female 1-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - other effects Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 279,1237,1996

Symbol	GHS09
Signal Word	Danger
Hazard Statements	H411
Precautionary Statements	P273
Hazard Codes	Xn: Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	26-36
RIDADR	UN 2811
WGK Germany	3
RTECS	HQ4430000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2933990090

298-46-4

~88%

36507-30-9

Literature: KANDULA, Mahesh Patent: WO2013/167985 A1, 2013 ; Location in patent: Paragraph 00100; 00101 ;

298-46-4

36507-30-9

35079-97-1

Literature: Applied Catalysis A: General, , vol. 408, # 1-2 p. 25 - 30

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36507-30-9

52618-28-7

Literature: Journal of Pharmacy and Pharmacology, , vol. 36, # 12 p. 843 - 844

Precursor 1
298-46-4
DownStream 6
28721-07-5 104746-04-5 29331-92-8 68011-71-2
885-23-4 106680-74-4

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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