Chengdu Pukang Biotechnology Co., Ltd.
China
Product Name: Maleimide-PEG6-NHS Ester
Price: ￥Inquiry/10kg
Purity: 95.0%
Stocking Period: Inquiry
Contact: Lihua Yang

DC Chemicals Limited
China
Product Name: Mal-amido-PEG6-NHS
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: alpha-Maleimidopropionyl-oMega-succinimidyl-6(ethylene glycol)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

1137109-21-7

1137109-21-7 structure

1137109-21-7 structure

Name: Mal-amido-PEG6-NHS ester
Chemical Name: Mal-PEG6-NHS
CAS Number: 1137109-21-7
Molecular Formula: C₂₆H₃₉N₃O₁₃
Molecular Weight: 601.60000
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-03-14 08:00:00
Modify Date: 2024-01-05 18:00:56
Mal-amido-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Mal-PEG6-NHS
Synonyms	α-Maleimidopropionyl-ω-succinimidyl-6(ethylene glycol)

Description	Mal-amido-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₂₆H₃₉N₃O₁₃
Molecular Weight	601.60000
Exact Mass	601.24800
PSA	185.54000
Storage condition	-20°C

Hazard Codes	Xi
RIDADR	NONH for all modes of transport