2207-44-5

2207-44-5 structure

Name: NPAS3-IN-1
Chemical Name: 2-(5-nitrothiazol-2-ylthio)benzo[d]thiazole
CAS Number: 2207-44-5
Molecular Formula: C₁₀H₅N₃O₂S₃
Molecular Weight: 295.36100
Catalog: Research Areas Neurological Disease
Create Date: 2018-06-01 20:48:38
Modify Date: 2024-02-04 10:58:26
NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization and regulates NPAS3 transcription by disrupting the heterodimerization of NPAS3 with ARNT at the cellular level[1].

Name	2-(5-nitrothiazol-2-ylthio)benzo[d]thiazole
Synonyms	BI-87G3 2-(5-nitro-thiazol-2-ylsulfanyl)-benzothiazole 5'-Nitro-2'-thiazolyl-2-benzothiazolylsulfiol JNK INHIBITOR XI

Description	NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization and regulates NPAS3 transcription by disrupting the heterodimerization of NPAS3 with ARNT at the cellular level[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Li P, et al. Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT. Bioorg Chem. 2023 Oct;139:106676.