2207-44-5

2207-44-5 structure
2207-44-5 structure
  • Name: NPAS3-IN-1
  • Chemical Name: 2-(5-nitrothiazol-2-ylthio)benzo[d]thiazole
  • CAS Number: 2207-44-5
  • Molecular Formula: C10H5N3O2S3
  • Molecular Weight: 295.36100
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-06-01 20:48:38
  • Modify Date: 2024-02-04 10:58:26
  • NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization and regulates NPAS3 transcription by disrupting the heterodimerization of NPAS3 with ARNT at the cellular level[1].

Name 2-(5-nitrothiazol-2-ylthio)benzo[d]thiazole
Synonyms BI-87G3
2-(5-nitro-thiazol-2-ylsulfanyl)-benzothiazole
5'-Nitro-2'-thiazolyl-2-benzothiazolylsulfiol
JNK INHIBITOR XI
Description NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization and regulates NPAS3 transcription by disrupting the heterodimerization of NPAS3 with ARNT at the cellular level[1].
Related Catalog
References

[1]. Li P, et al. Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT. Bioorg Chem. 2023 Oct;139:106676.  

Molecular Formula C10H5N3O2S3
Molecular Weight 295.36100
Exact Mass 294.95400
PSA 153.38000
LogP 4.33540
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H319
Precautionary Statements P301 + P310-P305 + P351 + P338
RIDADR UN 2811 6.1 / PGIII