NPAS3-IN-1

Modify Date: 2024-02-04 10:58:26

NPAS3-IN-1 Structure
NPAS3-IN-1 structure
Common Name NPAS3-IN-1
CAS Number 2207-44-5 Molecular Weight 295.36100
Density N/A Boiling Point N/A
Molecular Formula C10H5N3O2S3 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

 Use of NPAS3-IN-1


NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization and regulates NPAS3 transcription by disrupting the heterodimerization of NPAS3 with ARNT at the cellular level[1].

 Names

Name 2-(5-nitrothiazol-2-ylthio)benzo[d]thiazole
Synonym More Synonyms

 NPAS3-IN-1 Biological Activity

Description NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization and regulates NPAS3 transcription by disrupting the heterodimerization of NPAS3 with ARNT at the cellular level[1].
Related Catalog
References

[1]. Li P, et al. Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT. Bioorg Chem. 2023 Oct;139:106676.  

 Chemical & Physical Properties

Molecular Formula C10H5N3O2S3
Molecular Weight 295.36100
Exact Mass 294.95400
PSA 153.38000
LogP 4.33540

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H319
Precautionary Statements P301 + P310-P305 + P351 + P338
RIDADR UN 2811 6.1 / PGIII

 Articles1

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 Synonyms

BI-87G3
2-(5-nitro-thiazol-2-ylsulfanyl)-benzothiazole
5'-Nitro-2'-thiazolyl-2-benzothiazolylsulfiol
JNK INHIBITOR XI