Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Tetrazine-Ph-NHCO-C3-NHS ester
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Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

1244040-64-9

1244040-64-9 structure

1244040-64-9 structure

Name: Tetrazine-Ph-NHCO-C3-NHS ester
Chemical Name: 2,5-dioxopyrrolidin-1-yl 5-((4-(1,2,4,5-tetrazin-3-yl)benzyl)amino)-5-oxopentanoate
CAS Number: 1244040-64-9
Molecular Formula: C₁₈H₁₈N₆O₅
Molecular Weight: 398.37300
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-04-06 11:05:54
Modify Date: 2025-08-27 09:15:27
Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2,5-dioxopyrrolidin-1-yl 5-((4-(1,2,4,5-tetrazin-3-yl)benzyl)amino)-5-oxopentanoate

Description	Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₈H₁₈N₆O₅
Molecular Weight	398.37300
Exact Mass	398.13400
PSA	144.34000
LogP	0.65610

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
RIDADR	NONH for all modes of transport

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