Name | (+/-)-ochromycinone |
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Synonyms |
ochromycinone
STA-021 Ochromycinon, 8-Hydroxy-3-methyl-1-oxo-1,2,3,4-tetrahydrobenz(a)anthrachinon Ochromycinon, 8-Hydroxy-3-methyl-1-oxo-1,2,3,4-tetrahydrobenz[a]anthrachinon STA-21 |
Description | Ochromycinone ((Rac)-STA-21) is a natural antibiotic and a STAT3 inhibitor. Ochromycinone can inhibits STAT3 DNA binding activity, STAT3 dimerization. Ochromycinone has anticancer and antimicrobial activity[1][2]. |
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Related Catalog | |
Target |
STAT3 |
In Vitro | STA-21 inhibits STAT3 DNA binding activity, STAT3 dimerization, and STAT3-dependent luciferase activity. Moreover, STA-21 reduces the survival of breast carcinoma cells with constitutive STAT3 signaling but has minimal effect on the cells in which constitutive STAT3 signaling is absent[2]. |
References |
Molecular Formula | C19H14O4 |
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Molecular Weight | 306.31200 |
Exact Mass | 306.08900 |
PSA | 71.44000 |
LogP | 2.93260 |
Storage condition | -20℃ |