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69176-51-8

69176-51-8 structure
69176-51-8 structure
  • Name: Tigloylgomisin P
  • Chemical Name: Schisantherin B
  • CAS Number: 69176-51-8
  • Molecular Formula: C28H34O9
  • Molecular Weight: 514.56400
  • Catalog: Natural product Lignans
  • Create Date: 2018-04-17 23:44:46
  • Modify Date: 2025-08-26 01:09:53
  • Tigloylgomisin P, a lignin, has anti-HIV activity with an EC50 of 37 μM. Tigloylgomisin P has anticancer effect[1][2].

Name Schisantherin B
Synonyms gomisin B
Gomisin B
2-BUTENOIC ACID,2-METHYL-,(5R,6R,7S,13AS)-5,6,7,8-TETRAHYDRO-6-HYDROXY-1,2,3,13-TETRAMETHOXY-6,7-DIMETHYLBENZO[3,4]CYCLOOCTA[1,2-F][1,3]BENZODIOXOL-5-YLESTER, (2E)-
Description Tigloylgomisin P, a lignin, has anti-HIV activity with an EC50 of 37 μM. Tigloylgomisin P has anticancer effect[1][2].
Related Catalog
In Vitro Tigloylgomisin P displays weak cytotoxicity against A549 cells (GI50=18.77 μM), epidermoid carcinoma of the nasopharynx (KB; GI50=13.91 μM)[1].
References

[1]. Yan Lu, et al. Cytotoxic and potential anticancer constituents from the stems of Schisandra pubescens. Pharm Biol. 2013 Sep;51(9):1204-7.

[2]. Min Chen, et al. Rubrisandrins A and B, lignans and related anti-HIV compounds from Schisandra rubriflora. J Nat Prod. 2006 Dec;69(12):1697-701.

Molecular Formula C28H34O9
Molecular Weight 514.56400
Exact Mass 514.22000
PSA 101.91000
LogP 4.61040
Hazard Codes Xi
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