4725-51-3
4725-51-3 structure
- Name: (3β,5α,6β)-Androstane-3,5,6-triol
- Chemical Name: 5α-androst-3β,5,6β-triol
- CAS Number: 4725-51-3
- Molecular Formula: C19H32O3
- Molecular Weight: 308.456
- Catalog: Signaling Pathways Epigenetics AMPK
- Create Date: 2018-02-06 17:51:24
- Modify Date: 2024-01-17 18:16:25
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5α-Androstane-3β,5,6β-triol is a neuroprotectant. 5α-Androstane-3β,5,6β-triol can remarkably reverse intracellular acidification and alleviate neuronal injury through the inhibition of AMPK signaling. 5α-Androstane-3β,5,6β-triol remarkably reduced the infarct volume and attenuated neurologic impairment in acute ischemic stroke models of middle cerebral artery occlusion in vivo[1].
| Name | 5α-androst-3β,5,6β-triol |
|---|---|
| Synonyms |
androstane-3β,5α,6β-triol
Androstane-3,5,6-triol, (3β,5α,6β)- Androstan-3β,5α,6β-triol 5α-androstane-3β,5,6β-triol (3β,5α,6β)-Androstane-3,5,6-triol |
| Description | 5α-Androstane-3β,5,6β-triol is a neuroprotectant. 5α-Androstane-3β,5,6β-triol can remarkably reverse intracellular acidification and alleviate neuronal injury through the inhibition of AMPK signaling. 5α-Androstane-3β,5,6β-triol remarkably reduced the infarct volume and attenuated neurologic impairment in acute ischemic stroke models of middle cerebral artery occlusion in vivo[1]. |
|---|---|
| Related Catalog | |
| Target |
AMPK[1] |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 430.1±35.0 °C at 760 mmHg |
| Molecular Formula | C19H32O3 |
| Molecular Weight | 308.456 |
| Flash Point | 193.1±20.5 °C |
| Exact Mass | 308.235138 |
| PSA | 60.69000 |
| LogP | 3.88 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.580 |