(3β,5α,6β)-Androstane-3,5,6-triol

Modify Date: 2024-01-17 18:16:25

(3β,5α,6β)-Androstane-3,5,6-triol structure	Common Name	(3β,5α,6β)-Androstane-3,5,6-triol
	CAS Number	4725-51-3	Molecular Weight	308.456
	Density	1.2±0.1 g/cm3	Boiling Point	430.1±35.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₃₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	193.1±20.5 °C

Use of (3β,5α,6β)-Androstane-3,5,6-triol

5α-Androstane-3β,5,6β-triol is a neuroprotectant. 5α-Androstane-3β,5,6β-triol can remarkably reverse intracellular acidification and alleviate neuronal injury through the inhibition of AMPK signaling. 5α-Androstane-3β,5,6β-triol remarkably reduced the infarct volume and attenuated neurologic impairment in acute ischemic stroke models of middle cerebral artery occlusion in vivo[1].

Name	5α-androst-3β,5,6β-triol
Synonym	More Synonyms

Description	5α-Androstane-3β,5,6β-triol is a neuroprotectant. 5α-Androstane-3β,5,6β-triol can remarkably reverse intracellular acidification and alleviate neuronal injury through the inhibition of AMPK signaling. 5α-Androstane-3β,5,6β-triol remarkably reduced the infarct volume and attenuated neurologic impairment in acute ischemic stroke models of middle cerebral artery occlusion in vivo[1].
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Signaling Pathways >> PI3K/Akt/mTOR >> AMPK Research Areas >> Neurological Disease
Target	AMPK[1]
References	[1]. Xue D, et al. TRIOL Inhibits Rapid Intracellular Acidification and Cerebral Ischemic Injury: The Role of Glutamate in Neuronal Metabolic Reprogramming. ACS Chem Neurosci. 2022 Jun 30.

Density	1.2±0.1 g/cm3
Boiling Point	430.1±35.0 °C at 760 mmHg
Molecular Formula	C₁₉H₃₂O₃
Molecular Weight	308.456
Flash Point	193.1±20.5 °C
Exact Mass	308.235138
PSA	60.69000
LogP	3.88
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.580

androstane-3β,5α,6β-triol

Androstane-3,5,6-triol, (3β,5α,6β)-

Androstan-3β,5α,6β-triol

5α-androstane-3β,5,6β-triol

(3β,5α,6β)-Androstane-3,5,6-triol

DC Chemicals Limited
China
Product Name: Annaosanchun(YC-6)
Price: $500.0/100mg $950.0/250mg $1900.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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(3β,5α,6β)-Androstane-3,5,6-triol

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