18623-44-4

18623-44-4 structure

Name: iCRT-5
Chemical Name: iCRT5
CAS Number: 18623-44-4
Molecular Formula: C₁₆H₁₇NO₅S₂
Molecular Weight: 367.44000
Catalog: Research Areas Cancer
Create Date: 2018-03-24 12:09:23
Modify Date: 2025-08-26 14:48:27
iCRT-5 is a β-catenin-regulated transcription (CRT) inhibitor. iCRT-5 can block Wnt/β-catenin reporter activity and down regulate β-catenin expression. iCRT-5 can be used for the research of multiple myeloma[1][2].

Name	iCRT5

Description	iCRT-5 is a β-catenin-regulated transcription (CRT) inhibitor. iCRT-5 can block Wnt/β-catenin reporter activity and down regulate β-catenin expression. iCRT-5 can be used for the research of multiple myeloma[1][2].
Related Catalog	Research Areas >> Cancer
Target	β-catenin-regulated transcription (CRT)[1]
References	[1]. Käfer R, et, al. Inhibitors of β-catenin affect the immuno-phenotype and functions of dendritic cells in an inhibitor-specific manner. Int Immunopharmacol. 2016 Mar;32:118-124. [2]. Narayanan BA, et, al. Antagonistic effect of small-molecule inhibitors of Wnt/β-catenin in multiple myeloma. Anticancer Res. 2012 Nov;32(11):4697-707.