177951-34-7

177951-34-7 structure

Name: 3-(2-ETHYLPHENYL)-2-MERCAPTOQUINAZOLIN-4(3H)-ONE
Chemical Name: 3-(2-ethyl-phenyl)-2-thioxo-2,3-dihydro-1H-quinazolin-4-one
CAS Number: 177951-34-7
Molecular Formula: C₁₆H₁₄N₂OS
Molecular Weight: 282.36000
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-06-07 16:29:45
Modify Date: 2024-03-08 23:45:00
Anticancer agent 173 (compound 19) is a potent thioxodihydroquinazolinone analogs when combined with platinum drugs in inducing apoptotic cancer cells death[1].

Name	3-(2-ethyl-phenyl)-2-thioxo-2,3-dihydro-1H-quinazolin-4-one
Synonyms	3-(2-ethylphenyl)-2-mercaptoquinazolin-4(3h)-one

Description	Anticancer agent 173 (compound 19) is a potent thioxodihydroquinazolinone analogs when combined with platinum drugs in inducing apoptotic cancer cells death[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Jing Ma, et al. Combination of a thioxodihydroquinazolinone with cisplatineliminates ovarian cancer stem cell-like cells (CSC-LCs) andshows preclinical potential. Oncotarget. 2017 Dec 26;9(5):6042-6054.