3-(2-ETHYLPHENYL)-2-MERCAPTOQUINAZOLIN-4(3H)-ONE

Modify Date: 2024-03-08 23:45:00

3-(2-ETHYLPHENYL)-2-MERCAPTOQUINAZOLIN-4(3H)-ONE Structure
3-(2-ETHYLPHENYL)-2-MERCAPTOQUINAZOLIN-4(3H)-ONE structure
Common Name 3-(2-ETHYLPHENYL)-2-MERCAPTOQUINAZOLIN-4(3H)-ONE
CAS Number 177951-34-7 Molecular Weight 282.36000
Density N/A Boiling Point N/A
Molecular Formula C16H14N2OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3-(2-ETHYLPHENYL)-2-MERCAPTOQUINAZOLIN-4(3H)-ONE


Anticancer agent 173 (compound 19) is a potent thioxodihydroquinazolinone analogs when combined with platinum drugs in inducing apoptotic cancer cells death[1].

 Names

Name 3-(2-ethyl-phenyl)-2-thioxo-2,3-dihydro-1H-quinazolin-4-one
Synonym More Synonyms

  Biological Activity

Description Anticancer agent 173 (compound 19) is a potent thioxodihydroquinazolinone analogs when combined with platinum drugs in inducing apoptotic cancer cells death[1].
Related Catalog
References

[1]. Jing Ma, et al. Combination of a thioxodihydroquinazolinone with cisplatineliminates ovarian cancer stem cell-like cells (CSC-LCs) andshows preclinical potential. Oncotarget. 2017 Dec 26;9(5):6042-6054.  

 Chemical & Physical Properties

Molecular Formula C16H14N2OS
Molecular Weight 282.36000
Exact Mass 282.08300
PSA 69.88000
LogP 3.61070

 Synonyms

3-(2-ethylphenyl)-2-mercaptoquinazolin-4(3h)-one