882755-95-5

882755-95-5 structure

Name: MB-07729
Chemical Name: {5-[2-amino-5-(2,2-dimethyl-propionyl)-thiazol-4-yl]-furan-2-yl}-phosphonic acid
CAS Number: 882755-95-5
Molecular Formula: C₁₂H₁₅N₂O₅PS
Molecular Weight: 330.29700
Catalog: Research Areas Metabolic Disease
Create Date: 2018-06-22 05:36:58
Modify Date: 2024-01-08 13:40:56
MB-07729 is a potent fructose 1,6-bisphosphatase (FBPase) noncompetitive inhibitor with IC50 values of 31, 121, and 189 nM for human, monkey, and rat, respectively.

Name	{5-[2-amino-5-(2,2-dimethyl-propionyl)-thiazol-4-yl]-furan-2-yl}-phosphonic acid
Synonyms	{5-[2-amino-5-(2,2-dimethylpropionyl)thiazol-4-yl]furan-2-yl}phosphonic acid {5-[2-amino-5-(2,2-dimethylpropionyl)thiazol-4-yl]-furan-2-yl}phosphonic acid

Description	MB-07729 is a potent fructose 1,6-bisphosphatase (FBPase) noncompetitive inhibitor with IC50 values of 31, 121, and 189 nM for human, monkey, and rat, respectively.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	31, 121, and 189 nM for human, monkey, and rat, respectively [1] .
References	[1]. PAUL D. VAN POELJE，et al. MB07803, a Prodrug of a Second Generation Fructose-1,6-Bisphosphatase Inhibitor, Lowers Blood Glucose in Diabetic Rodents and in Cynomolgus Monkeys.