MB-07729

Modify Date: 2024-01-08 13:40:56

MB-07729 Structure
MB-07729 structure
Common Name MB-07729
CAS Number 882755-95-5 Molecular Weight 330.29700
Density N/A Boiling Point N/A
Molecular Formula C12H15N2O5PS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MB-07729


MB-07729 is a potent fructose 1,6-bisphosphatase (FBPase) noncompetitive inhibitor with IC50 values of 31, 121, and 189 nM for human, monkey, and rat, respectively.

 Names

Name {5-[2-amino-5-(2,2-dimethyl-propionyl)-thiazol-4-yl]-furan-2-yl}-phosphonic acid
Synonym More Synonyms

 MB-07729 Biological Activity

Description MB-07729 is a potent fructose 1,6-bisphosphatase (FBPase) noncompetitive inhibitor with IC50 values of 31, 121, and 189 nM for human, monkey, and rat, respectively.
Related Catalog
Target

31, 121, and 189 nM for human, monkey, and rat, respectively [1] .

References

[1]. PAUL D. VAN POELJE,et al. MB07803, a Prodrug of a Second Generation Fructose-1,6-Bisphosphatase Inhibitor, Lowers Blood Glucose in Diabetic Rodents and in Cynomolgus Monkeys.

 Chemical & Physical Properties

Molecular Formula C12H15N2O5PS
Molecular Weight 330.29700
Exact Mass 330.04400
PSA 164.70000
LogP 2.59830

 Synonyms

{5-[2-amino-5-(2,2-dimethylpropionyl)thiazol-4-yl]furan-2-yl}phosphonic acid
{5-[2-amino-5-(2,2-dimethylpropionyl)thiazol-4-yl]-furan-2-yl}phosphonic acid