83-85-2

83-85-2 structure

Name: Fuscin
Chemical Name: 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione
CAS Number: 83-85-2
Molecular Formula: C₁₅H₁₆O₅
Molecular Weight: 276.28500
Catalog: Organic raw materials Organic phosphine compound
Create Date: 2017-07-23 10:36:49
Modify Date: 2024-01-05 18:59:31
Fuscin, a fungal metabolite, CCR5 receptor antagonist with anti-HIV effects. Fuscin is a respiration and oxidative phosphorylation inhibitor, and also a mitochondrial SH-dependent transport-linked functions inhibitor[1][2][3].

Name	5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione
Synonyms	5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H,8H-pyrano[4,3-f]chromene-2,6-dione 2H,4H-Benzo(1,2-b:4,3-c')dipyran-2,6(8H)-dione,9,10-dihydro-5-hydroxy-4,8,8-trimethyl 2-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-5,6-dione 2-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H,5H-pyrano[4,3-f]chromene-5,6(8H)-dione fuscin (9,10-dihydro-5-hydroxy-4,8,8-trimethyl-2H,4H-benzo<1,2-b,4,3-c'>dipyran-2,6(8H)dione) Fuscin 9,10-Dihydro-5-hydroxy-4,8,8-trimethyl-2-H,4-H-benzo(1,2-b-4,3-c)-dipyran-2,6(8H)-dione

Description	Fuscin, a fungal metabolite, CCR5 receptor antagonist with anti-HIV effects. Fuscin is a respiration and oxidative phosphorylation inhibitor, and also a mitochondrial SH-dependent transport-linked functions inhibitor[1][2][3].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CCR Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Immunology/Inflammation >> CCR Research Areas >> Metabolic Disease Signaling Pathways >> Anti-infection >> Bacterial
Target	HIV CCR5 Microbial Metabolite
References	[1]. K Yoganathan, et al. 10-Methoxydihydrofuscin, fuscinarin, and fuscin, novel antagonists of the human CCR5 receptor from Oidiodendron griseum. J Nat Prod. 2003 Aug;66(8):1116-7. [2]. K S Cheah. Fuscin, an inhibitor of respiration and oxidative phosphorylation in ox-neck muscle mitochondria. Biochim Biophys Acta.1972 Jul 12;275(1):1-9. [3]. P M Vignais, et al. Fuscin, an inhibitor of mitochondrial SH-dependent transport-linked functions. Biochim Biophys Acta. 1973 Dec 14;325(3):357-74.

HS Code	2932999099

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%