Fuscin

Modify Date: 2026-06-30 16:51:36

Fuscin Structure
Fuscin structure
Common Name Fuscin
CAS Number 83-85-2 Molecular Weight 276.28500
Density 1.35g/cm3 Boiling Point 417.6ºC at 760 mmHg
Molecular Formula C15H16O5 Melting Point N/A
MSDS N/A Flash Point 155.5ºC

 Use of Fuscin


Fuscin, a fungal metabolite, CCR5 receptor antagonist with anti-HIV effects. Fuscin is a respiration and oxidative phosphorylation inhibitor, and also a mitochondrial SH-dependent transport-linked functions inhibitor[1][2][3].

Summary: Fuscin, Chinese name: 褐藻胶, CAS number: 83-85-2, molecular formula: C15H16O5, molecular weight: 276.28500. For research-use only, not for medical or clinical usage.


 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione
Synonym More Synonyms

 Fuscin Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Fuscin, a fungal metabolite, CCR5 receptor antagonist with anti-HIV effects. Fuscin is a respiration and oxidative phosphorylation inhibitor, and also a mitochondrial SH-dependent transport-linked functions inhibitor[1][2][3].
Related Catalog
Target

HIV

CCR5

Microbial Metabolite

References

[1]. K Yoganathan, et al. 10-Methoxydihydrofuscin, fuscinarin, and fuscin, novel antagonists of the human CCR5 receptor from Oidiodendron griseum. J Nat Prod. 2003 Aug;66(8):1116-7.

[2]. K S Cheah. Fuscin, an inhibitor of respiration and oxidative phosphorylation in ox-neck muscle mitochondria. Biochim Biophys Acta.1972 Jul 12;275(1):1-9.

[3]. P M Vignais, et al. Fuscin, an inhibitor of mitochondrial SH-dependent transport-linked functions. Biochim Biophys Acta. 1973 Dec 14;325(3):357-74.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.35g/cm3
Boiling Point 417.6ºC at 760 mmHg
Molecular Formula C15H16O5
Molecular Weight 276.28500
Flash Point 155.5ºC
Exact Mass 276.10000
PSA 72.83000
LogP 2.09600
Index of Refraction 1.594

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

HS Code 2932999099

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H,8H-pyrano[4,3-f]chromene-2,6-dione
2H,4H-Benzo(1,2-b:4,3-c')dipyran-2,6(8H)-dione,9,10-dihydro-5-hydroxy-4,8,8-trimethyl
2-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-5,6-dione
2-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H,5H-pyrano[4,3-f]chromene-5,6(8H)-dione
fuscin (9,10-dihydro-5-hydroxy-4,8,8-trimethyl-2H,4H-benzo<1,2-b,4,3-c'>dipyran-2,6(8H)dione)
Fuscin
9,10-Dihydro-5-hydroxy-4,8,8-trimethyl-2-H,4-H-benzo(1,2-b-4,3-c)-dipyran-2,6(8H)-dione

 Fuscin | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the CAS number of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione?
A: CAS number of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione is 83-85-2.
Q: What is the molecular weight of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione?
A: Molecular weight of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione is 276.28500.
Q: What is the boiling point of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione?
A: Boiling point of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione is 417.6ºC at 760 mmHg.
Q: What is the polar surface area (PSA) of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione?
A: Polar surface area (PSA) of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione is 72.83000.
Q: What is the English name of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione?
A: The English name of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione is 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione.
Q: What is the molecular formula of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione?
A: Molecular formula of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione is C15H16O5.
Q: What are the uses of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione?
A: Main uses of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione: Fuscin, a fungal metabolite, CCR5 receptor antagonist with anti-HIV effects. Fuscin is a respiration and oxidative phosphorylation inhibitor, and also a mitochondrial SH-dependent transport-linked functions inhibitor[1][2][3].
Q: What is the LogP of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione?
A: LogP of 5-hydroxy-4,8,8-trimethyl-9,10-dihydro-4H-pyrano[4,3-f]chromene-2,6-dione is 2.09600.

 Fuscinfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

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