74805-91-7

74805-91-7 structure

Name: Methylophiopogonanone B
Chemical Name: (3R)-5,7-Dihydroxy-3-(4-methoxybenzyl)-6,8-dimethyl-2,3-dihydro-4 H-chromen-4-one
CAS Number: 74805-91-7
Molecular Formula: C₁₉H₂₀O₅
Molecular Weight: 328.359
Catalog: Natural product Flavonoids
Create Date: 2018-08-27 15:23:51
Modify Date: 2024-01-02 17:25:14
Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas, shows high antioxidant ability[1]. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation[2].

Name	(3R)-5,7-Dihydroxy-3-(4-methoxybenzyl)-6,8-dimethyl-2,3-dihydro-4 H-chromen-4-one
Synonyms	methylophiopogonanone B Methyl o-nitrophenylacetate 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6,8-dimethyl-, (3R)- 2-nitrophenylacetic acid methyl ester (3R)-5,7-Dihydroxy-3-(4-methoxybenzyl)-6,8-dimethyl-2,3-dihydro-4H-chromen-4-one

Description	Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas, shows high antioxidant ability[1]. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation[2].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> Ras
References	[1]. Wang Y, et al. Homoisoflavonoids and the Antioxidant Activity of Ophiopogon japonicus Root. [2]. Ito Y, et al. A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization. Mol Cell Biochem. 2007 Mar;297(1-2):121-9. Epub 2006 Oct 7.

Hazard Codes	Xi