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  • Product Name: AM 6201
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68748-55-0

68748-55-0 structure
68748-55-0 structure
  • Name: AM 6201
  • Chemical Name: 4-{(1E)-3-[(2-Hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-3-oxo-1-pro pen-1-yl}-2,3-dihydro-2-furanyl acetate
  • CAS Number: 68748-55-0
  • Molecular Formula: C14H15NO6
  • Molecular Weight: 293.27200
  • Create Date: 2016-04-28 21:43:13
  • Modify Date: 2024-01-10 16:30:51
  • AM 6201, also known as Reductiomycin, is an alkaloid originally derived from Streptomyces xanthochromogenus that has been shown to exhibit antitumor activity against Ehrlich ascites carcinomas in mice.

Name 4-{(1E)-3-[(2-Hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-3-oxo-1-pro pen-1-yl}-2,3-dihydro-2-furanyl acetate
Synonyms tert-Butyl(phenyl)phosphine oxide
(+/-)-tert-butyl(phenyl)phosphane oxide
reductiomycin
Phosphine oxide,(1,1-dimethylethyl)phenyl
(t-butyl-phenyl) H phosphinate
(+/-)-P-t-butyl-P-phenylphosphane oxide
2-3'-2''-acetoxy-2'',3'',-dihydrofur-4''-ylacrylamido-3-hydroxy-2-cyclopenten-1-one
Density 1.39g/cm3
Boiling Point 522.8ºC at 760 mmHg
Molecular Formula C14H15NO6
Molecular Weight 293.27200
Flash Point 270ºC
Exact Mass 293.09000
PSA 105.42000
LogP 1.82500
Index of Refraction 1.587

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UC6220000
CHEMICAL NAME :
2-Propenamide, 3-(5-(acetyloxy)-4,5-dihydro-3-furanyl)-N-(2-hydroxy- 5-oxo-1-cyclopenten-1- yl)-, (E)-(+)-
CAS REGISTRY NUMBER :
68748-55-0
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H15-N-O6
MOLECULAR WEIGHT :
293.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 34,649,1981