25695-95-8

25695-95-8 structure

Name: (2S,3S,4E)-2-Amino-4-octadecene-1,3-diol
Chemical Name: (2S,3S,4E)-L-threo sphingosine
CAS Number: 25695-95-8
Molecular Formula: C₁₈H₃₇NO₂
Molecular Weight: 299.492
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-06-23 16:11:38
Modify Date: 2025-08-24 23:23:51
L-threo-Sphingosine is a potent MAPK inhibitor. L-threo-Sphingosine induces apoptosis and clear DNA fragmentation. L-threo-Sphingosine shows anticancer effect[1].

Name	(2S,3S,4E)-L-threo sphingosine
Synonyms	(2S,3S,4E)-2-Amino-octadec-4-ene-1,3-diol L-(-)-Threosphingenine (2S,3S,4E)-L-threo-sphingosine L-threo-sphingosine 4-Octadecene-1,3-diol, 2-amino-, (2S,3S,4E)- (-)-(E,2S,3S)-2-aminooctadec-4-ene-1,3-diol (2S,3S,4E)-2-Amino-4-octadecene-1,3-diol (E)-(2S,3S)-2-Amino-octadec-4-ene-1,3-diol (2S,3S,4E)-2-aminooctadec-4-ene-1,3-diol

Description	L-threo-Sphingosine is a potent MAPK inhibitor. L-threo-Sphingosine induces apoptosis and clear DNA fragmentation. L-threo-Sphingosine shows anticancer effect[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK
References	[1]. Sakakura C, et al. Selectivity of sphingosine-induced apoptosis. Lack of activity of DL-erythyro-dihydrosphingosine. Biochem Biophys Res Commun. 1998 May 29;246(3):827-30.