23173-26-4

23173-26-4 structure

Name: Apovincaminol
Chemical Name: eburnamenine-14-ylmethanol
CAS Number: 23173-26-4
Molecular Formula: C₂₀H₂₄N₂O
Molecular Weight: 308.42
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-02-26 06:56:21
Modify Date: 2025-08-25 11:43:10
Vin-C01 is a potent pancreatic β-cells protective agent with an EC50 of 0.22 µM. Vin-C01 effectively promotes β-cell survival and protects β-cells from STZ-induced apoptosis. Vin-C01 can be used for type 2 diabetes mellitus research[1].

Name	eburnamenine-14-ylmethanol
Synonyms	((11aS,11bS)-11a-Ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthen-10-yl)-methanol

Description	Vin-C01 is a potent pancreatic β-cells protective agent with an EC50 of 0.22 µM. Vin-C01 effectively promotes β-cell survival and protects β-cells from STZ-induced apoptosis. Vin-C01 can be used for type 2 diabetes mellitus research[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cardiovascular Disease
Target	EC50: 0.22 µM (pancreatic β-cells)[1]
References	[1]. Wang J, et al. Design, synthesis and biological evaluation of vincamine derivatives as potential pancreatic β-cells protective agents for the treatment of type 2 diabetes mellitus. Eur J Med Chem. 2020 Feb 15;188:111976.