Apovincaminol

Modify Date: 2024-03-31 18:06:46

Apovincaminol Structure
Apovincaminol structure
Common Name Apovincaminol
CAS Number 23173-26-4 Molecular Weight 308.42
Density N/A Boiling Point N/A
Molecular Formula C20H24N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Apovincaminol


Vin-C01 is a potent pancreatic β-cells protective agent with an EC50 of 0.22 µM. Vin-C01 effectively promotes β-cell survival and protects β-cells from STZ-induced apoptosis. Vin-C01 can be used for type 2 diabetes mellitus research[1].

 Names

Name eburnamenine-14-ylmethanol
Synonym More Synonyms

 Apovincaminol Biological Activity

Description Vin-C01 is a potent pancreatic β-cells protective agent with an EC50 of 0.22 µM. Vin-C01 effectively promotes β-cell survival and protects β-cells from STZ-induced apoptosis. Vin-C01 can be used for type 2 diabetes mellitus research[1].
Related Catalog
Target

EC50: 0.22 µM (pancreatic β-cells)[1]

References

[1]. Wang J, et al. Design, synthesis and biological evaluation of vincamine derivatives as potential pancreatic β-cells protective agents for the treatment of type 2 diabetes mellitus. Eur J Med Chem. 2020 Feb 15;188:111976.

 Chemical & Physical Properties

Molecular Formula C20H24N2O
Molecular Weight 308.42
Exact Mass 308.18900
PSA 28.40000
LogP 3.51540

 Synonyms

((11aS,11bS)-11a-Ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthen-10-yl)-methanol