5943-17-9

5943-17-9 structure
5943-17-9 structure
  • Name: Tetraethyl heptane-1,7-diylbis(phosphonate)
  • Chemical Name: Methyl 2-{[(2-methoxybenzoyl)(propyl)amino]methyl}-1,3-oxazole-4- carboxylate
  • CAS Number: 5943-17-9
  • Molecular Formula: C15H34O6P2
  • Molecular Weight: 332.35100
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-10-17 19:03:17
  • Modify Date: 2024-01-12 16:45:11
  • Tetraethyl heptane-1,7-diylbis(phosphonate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Methyl 2-{[(2-methoxybenzoyl)(propyl)amino]methyl}-1,3-oxazole-4- carboxylate
Synonyms MFCD24539458
Description Tetraethyl heptane-1,7-diylbis(phosphonate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.202g/cm3
Boiling Point 494.4ºC at 760mmHg
Molecular Formula C15H34O6P2
Molecular Weight 332.35100
Flash Point 252.8ºC
Exact Mass 332.13700
PSA 81.87000
LogP 2.52220
Index of Refraction 1.543