5943-17-9

5943-17-9 structure

Name: Tetraethyl heptane-1,7-diylbis(phosphonate)
Chemical Name: Methyl 2-{[(2-methoxybenzoyl)(propyl)amino]methyl}-1,3-oxazole-4- carboxylate
CAS Number: 5943-17-9
Molecular Formula: C₁₅H₃₄O₆P₂
Molecular Weight: 332.35100
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-10-17 19:03:17
Modify Date: 2024-01-12 16:45:11
Tetraethyl heptane-1,7-diylbis(phosphonate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Methyl 2-{[(2-methoxybenzoyl)(propyl)amino]methyl}-1,3-oxazole-4- carboxylate
Synonyms	MFCD24539458

Description	Tetraethyl heptane-1,7-diylbis(phosphonate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

4549-31-9

122-52-1

5943-17-9

Literature: Kosolapoff,G.M.; Brown,A.D. Journal of the Chemical Society [Section] C: Organic, 1966 , p. 757 - 759