125708-06-7

125708-06-7 structure

Name: Lyciumin A
Chemical Name: lyciumin A
CAS Number: 125708-06-7
Molecular Formula: C₄₂H₅₁N₉O₁₂
Molecular Weight: 873.90700
Catalog: Signaling Pathways Metabolic Enzyme/Protease Angiotensin-converting Enzyme (ACE)
Create Date: 2018-02-09 23:34:43
Modify Date: 2024-01-02 19:29:42
Lyciumin A, a cyclic octapeptide, exhibits inhibitory activity on proteases, renin and angiotensin-converting enzyme. Lyciumin A can be used for the research of hypertension[1][2].

Name	lyciumin A

Description	Lyciumin A, a cyclic octapeptide, exhibits inhibitory activity on proteases, renin and angiotensin-converting enzyme. Lyciumin A can be used for the research of hypertension[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE) Signaling Pathways >> Metabolic Enzyme/Protease >> Renin
Target	proteases[2], renin[2], angiotensin-converting enzyme[2]
In Vitro	Lyciumin A inhibits renin activities by 19.4% (40 μg/mL).
References	[1]. Kersten RD, et, al. Gene-guided discovery and engineering of branched cyclic peptides in plants. Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):E10961-E10969. [2]. Rubin GM, et, al. Recent advances in the biosynthesis of RiPPs from multicore-containing precursor peptides. J Ind Microbiol Biotechnol. 2020 Oct;47(9-10):659-674.

Hazard Codes	Xi