104518-25-4

104518-25-4 structure
104518-25-4 structure
  • Name: m-PEG7-Br
  • Chemical Name: methoxy hepta(ethylene glycol)bromide
  • CAS Number: 104518-25-4
  • Molecular Formula: C15H31BrO7
  • Molecular Weight: 403.30600
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-04-12 08:00:00
  • Modify Date: 2024-01-20 17:36:33
  • m-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name methoxy hepta(ethylene glycol)bromide
Synonyms 1-{2-[2-(2-Bromo-ethoxy)-ethoxy]-ethoxy}-2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethane
m-PEG-7-Br
mPEG7-Br
m-PEG-7-bromide
Description m-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C15H31BrO7
Molecular Weight 403.30600
Exact Mass 402.12500
PSA 64.61000
LogP 1.12730
Hazard Codes Xi