m-PEG7-Br

Modify Date: 2024-01-20 17:36:33

m-PEG7-Br Structure
m-PEG7-Br structure
Common Name m-PEG7-Br
CAS Number 104518-25-4 Molecular Weight 403.30600
Density N/A Boiling Point N/A
Molecular Formula C15H31BrO7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG7-Br


m-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name methoxy hepta(ethylene glycol)bromide
Synonym More Synonyms

 m-PEG7-Br Biological Activity

Description m-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C15H31BrO7
Molecular Weight 403.30600
Exact Mass 402.12500
PSA 64.61000
LogP 1.12730

 Safety Information

Hazard Codes Xi

 Synonyms

1-{2-[2-(2-Bromo-ethoxy)-ethoxy]-ethoxy}-2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethane
m-PEG-7-Br
mPEG7-Br
m-PEG-7-bromide