68960-97-4

68960-97-4 structure

Name: Amino-PEG4-C2-amine
Chemical Name: 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethanamine
CAS Number: 68960-97-4
Molecular Formula: C₁₀H₂₄N₂O₄
Molecular Weight: 236.30900
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-10-16 06:53:56
Modify Date: 2024-01-11 15:29:44
Amino-PEG4-C2-amine is a PEG-based (4 units) PROTAC linker can be used in the synthesis of PROTACs.

Name	2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethanamine
Synonyms	1,14-diamino-3,6,9,12-tetraoxatetradecane 3,6,9,12-Tetraoxatetradecane-1,14-diamine

Description	Amino-PEG4-C2-amine is a PEG-based (4 units) PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

Hazard Class	8.0

70110-27-9

~89%

68960-97-4

Literature: Liu, Kun; Meyerhoff, Mark E. Journal of Materials Chemistry, 2012 , vol. 22, # 36 p. 18784 - 18787

5197-65-9

68960-97-4

Literature: Ciuffarin, Ennio; Isola, Mauro; Leoni, Piero Journal of Organic Chemistry, 1981 , vol. 46, # 15 p. 3064 - 3070