68960-97-4
68960-97-4 structure
- Name: Amino-PEG4-C2-amine
- Chemical Name: 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethanamine
- CAS Number: 68960-97-4
- Molecular Formula: C10H24N2O4
- Molecular Weight: 236.30900
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-10-16 06:53:56
- Modify Date: 2024-01-11 15:29:44
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Amino-PEG4-C2-amine is a PEG-based (4 units) PROTAC linker can be used in the synthesis of PROTACs.
| Name | 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethanamine |
|---|---|
| Synonyms |
1,14-diamino-3,6,9,12-tetraoxatetradecane
3,6,9,12-Tetraoxatetradecane-1,14-diamine |
| Description | Amino-PEG4-C2-amine is a PEG-based (4 units) PROTAC linker can be used in the synthesis of PROTACs. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Boiling Point | 139 °C/0.2 mmHg |
|---|---|
| Molecular Formula | C10H24N2O4 |
| Molecular Weight | 236.30900 |
| Flash Point | 157 °C |
| Exact Mass | 236.17400 |
| PSA | 88.96000 |
| LogP | 0.37080 |
| Index of Refraction | 1.47 |
| Hazard Class | 8.0 |
|---|
|
~89%
68960-97-4 |
| Literature: Liu, Kun; Meyerhoff, Mark E. Journal of Materials Chemistry, 2012 , vol. 22, # 36 p. 18784 - 18787 |
|
~%
68960-97-4 |
| Literature: Ciuffarin, Ennio; Isola, Mauro; Leoni, Piero Journal of Organic Chemistry, 1981 , vol. 46, # 15 p. 3064 - 3070 |
| Precursor 2 | |
|---|---|
| DownStream 3 | |
