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811442-84-9

811442-84-9 structure
811442-84-9 structure
  • Name: Boc-NH-PEG4-CH2CH2NH2
  • Chemical Name: tert-Butyl (14-amino-3,6,9,12-tetraoxatetradecyl)carbamate
  • CAS Number: 811442-84-9
  • Molecular Formula: C15H32N2O6
  • Molecular Weight: 336.42400
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-12-23 20:16:47
  • Modify Date: 2024-01-11 11:09:50
  • Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name tert-Butyl (14-amino-3,6,9,12-tetraoxatetradecyl)carbamate
Synonyms tert-butyl N-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate
Description Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Hans-Georg Lerchen, et al. Preparation of antibody drug conjugates of kinesin spindle protein (KSP) inhibitors with anti-TWEAKR-antibodies. WO2016207094A1.

Density 1.059
Molecular Formula C15H32N2O6
Molecular Weight 336.42400
Flash Point 222 °C
Exact Mass 336.22600
PSA 101.27000
LogP 1.62740
Hazard Codes Xi
HS Code 2924199090

~64%

811442-84-9 structure

811442-84-9

Literature: Ishida, Manabu; Watanabe, Hideaki; Takigawa, Kazumasa; Kurishita, Yasutaka; Oki, Choji; Nakamura, Akinobu; Hamachi, Itaru; Tsukiji, Shinya Journal of the American Chemical Society, 2013 , vol. 135, # 34 p. 12684 - 12689
Precursor  2

DownStream  0

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%