Name | tert-Butyl (14-amino-3,6,9,12-tetraoxatetradecyl)carbamate |
---|---|
Synonyms | tert-butyl N-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate |
Description | Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
---|---|
Related Catalog | |
Target |
Cleavable |
In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
References |
Density | 1.059 |
---|---|
Molecular Formula | C15H32N2O6 |
Molecular Weight | 336.42400 |
Flash Point | 222 °C |
Exact Mass | 336.22600 |
PSA | 101.27000 |
LogP | 1.62740 |
Hazard Codes | Xi |
---|---|
HS Code | 2924199090 |
~64% 811442-84-9 |
Literature: Ishida, Manabu; Watanabe, Hideaki; Takigawa, Kazumasa; Kurishita, Yasutaka; Oki, Choji; Nakamura, Akinobu; Hamachi, Itaru; Tsukiji, Shinya Journal of the American Chemical Society, 2013 , vol. 135, # 34 p. 12684 - 12689 |
Precursor 2 | |
---|---|
DownStream 0 |
HS Code | 2924199090 |
---|---|
Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |