| Name | tert-Butyl (14-amino-3,6,9,12-tetraoxatetradecyl)carbamate |
|---|---|
| Synonyms | tert-butyl N-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate |
| Description | Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
| Density | 1.059 |
|---|---|
| Molecular Formula | C15H32N2O6 |
| Molecular Weight | 336.42400 |
| Flash Point | 222 °C |
| Exact Mass | 336.22600 |
| PSA | 101.27000 |
| LogP | 1.62740 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2924199090 |
|
~64%
811442-84-9 |
| Literature: Ishida, Manabu; Watanabe, Hideaki; Takigawa, Kazumasa; Kurishita, Yasutaka; Oki, Choji; Nakamura, Akinobu; Hamachi, Itaru; Tsukiji, Shinya Journal of the American Chemical Society, 2013 , vol. 135, # 34 p. 12684 - 12689 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |