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326886-05-9

326886-05-9 structure
326886-05-9 structure
  • Name: Shz 1
  • Chemical Name: N'-[(E)-(5-Bromo-2-hydroxyphenyl)methylene]benzenesulfonohydrazide
  • CAS Number: 326886-05-9
  • Molecular Formula: C13H11BrN2O3S
  • Molecular Weight: 355.207
  • Catalog: Research Areas Cardiovascular Disease
  • Create Date: 2018-06-10 17:43:30
  • Modify Date: 2025-08-24 21:37:01
  • Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells[1].

Name N'-[(E)-(5-Bromo-2-hydroxyphenyl)methylene]benzenesulfonohydrazide
Synonyms N'-[(E)-(5-Bromo-2-hydroxyphenyl)methylene]benzenesulfonohydrazide
Benzenesulfonic acid, 2-[(1E)-(5-bromo-2-hydroxyphenyl)methylene]hydrazide
Shz-1
Description Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells[1].
Related Catalog
References

[1]. Changlong Nan, et al. Expression of sarcomeric tropomyosin in striated muscles in axolotl treated with shz-1, a small cardiogenic molecule. Cardiovasc Toxicol. 2015 Jan;15(1):29-40.

Density 1.6±0.1 g/cm3
Boiling Point 503.9±60.0 °C at 760 mmHg
Molecular Formula C13H11BrN2O3S
Molecular Weight 355.207
Flash Point 258.5±32.9 °C
Exact Mass 353.967377
LogP 4.07
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.648
Storage condition -20°C
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi
RIDADR NONH for all modes of transport
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