Shz 1

Modify Date: 2024-01-03 11:07:16

Shz 1 Structure
Shz 1 structure
Common Name Shz 1
CAS Number 326886-05-9 Molecular Weight 355.207
Density 1.6±0.1 g/cm3 Boiling Point 503.9±60.0 °C at 760 mmHg
Molecular Formula C13H11BrN2O3S Melting Point N/A
MSDS Chinese USA Flash Point 258.5±32.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Shz 1


Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells[1].

 Names

Name N'-[(E)-(5-Bromo-2-hydroxyphenyl)methylene]benzenesulfonohydrazide
Synonym More Synonyms

 Shz 1 Biological Activity

Description Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells[1].
Related Catalog
References

[1]. Changlong Nan, et al. Expression of sarcomeric tropomyosin in striated muscles in axolotl treated with shz-1, a small cardiogenic molecule. Cardiovasc Toxicol. 2015 Jan;15(1):29-40.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 503.9±60.0 °C at 760 mmHg
Molecular Formula C13H11BrN2O3S
Molecular Weight 355.207
Flash Point 258.5±32.9 °C
Exact Mass 353.967377
LogP 4.07
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.648
Storage condition -20°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi
RIDADR NONH for all modes of transport

 Synonyms

N'-[(E)-(5-Bromo-2-hydroxyphenyl)methylene]benzenesulfonohydrazide
Benzenesulfonic acid, 2-[(1E)-(5-bromo-2-hydroxyphenyl)methylene]hydrazide
Shz-1