75970-99-9

75970-99-9 structure

Name: norastemizole
Chemical Name: 1-[(4-fluorophenyl)methyl]-N-piperidin-4-ylbenzimidazol-2-amine
CAS Number: 75970-99-9
Molecular Formula: C₁₉H₂₁FN₄
Molecular Weight: 324.40
Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
Create Date: 2017-04-22 17:06:30
Modify Date: 2026-07-01 09:02:43
Tecastemizole (Norastemizole), a major metabolite of Astemizole, is a potent and selective H1 receptor antagonist. Tecastemizole shows anti-inflammatory activities[1].

Name	1-[(4-fluorophenyl)methyl]-N-piperidin-4-ylbenzimidazol-2-amine
Synonyms	T 1348 Norastemizole R-41232 N-(4-Piperidinyl)-1-(4-fluorobenzyl)-1H-benzoimidazole-2-amine 1-(4-FLUOROBENZYL)-1H-BENZIMIDAZOL-2-YL](4-PIPERIDYL)AMINE anti-inflammatory,Inhibitor,allergy,Histamine Rector,inhibit,Tecastemizole 1-(4-Fluorobenzyl)-N-(piperidin-4-yl)-1H-benzo[d]imidazol-2-amine Norastemizole/Tecastemizole [1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-piperidin-4-yl-amine 1H-Benzimidazol-2-amine, 1-[(4-fluorophenyl)methyl]-N-4-piperidinyl 1-[(4-Fluorophenyl)methyl]-N-(4-piperidinyl)-1H-benzimidazol-2-amine 1-[(4-fluorophenyl)methyl]-N-(piperidin-4-yl)-1H-1,3-benzodiazol-2-amine Tecastemizole, 10 mM in DMSO 1-[(4-fluorophenyl)methyl]-N-(piperidin-4-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-imine Tetemizole Soltara

Description	Tecastemizole (Norastemizole), a major metabolite of Astemizole, is a potent and selective H1 receptor antagonist. Tecastemizole shows anti-inflammatory activities[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
References	[1]. Lever R, et al. Effect of tecastemizole on pulmonary and cutaneous allergic inflammatory responses. Clin Exp Allergy. 2007 Jun;37(6):909-17.