1219803-50-5

1219803-50-5 structure

Name: Dimethyl biphenyl-4,4'-dicarboxylate-d8
Chemical Name: Dimethyl 4,4'-(2H8)biphenyldicarboxylate
CAS Number: 1219803-50-5
Molecular Formula: C₁₆H₆D₈O₄
Molecular Weight: 278.329
Catalog: Research Areas Metabolic Disease
Create Date: 2018-01-28 20:47:41
Modify Date: 2024-01-20 09:58:13
Dimethyl biphenyl-4,4'-dicarboxylate-d8 is the deuterium labeled Dimethyl biphenyl-4,4'-dicarboxylate[1]. Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a hepatoprotectant obtained from Schizandra fructus and may induce a signal transduction similar to that associated with IFN[2].

Name	Dimethyl 4,4'-(2H8)biphenyldicarboxylate
Synonyms	[1,1'-Biphenyl-d]-4,4'-dicarboxylic acid, dimethyl ester Dimethyl 4,4'-(H)biphenyldicarboxylate Dimethyl (H)biphenyl-4,4'-dicarboxylate

Description	Dimethyl biphenyl-4,4'-dicarboxylate-d8 is the deuterium labeled Dimethyl biphenyl-4,4'-dicarboxylate[1]. Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a hepatoprotectant obtained from Schizandra fructus and may induce a signal transduction similar to that associated with IFN[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Joo SS, et al. Interferon signal transduction of biphenyl dimethyl dicarboxylate/amantadine and anti-HBV activity in HepG2 2.2.15. Arch Pharm Res. 2006 May;29(5):405-11.