Dimethyl biphenyl-4,4'-dicarboxylate-d8

Modify Date: 2024-01-20 09:58:13

Dimethyl biphenyl-4,4'-dicarboxylate-d8 Structure
Dimethyl biphenyl-4,4'-dicarboxylate-d8 structure
Common Name Dimethyl biphenyl-4,4'-dicarboxylate-d8
CAS Number 1219803-50-5 Molecular Weight 278.329
Density 1.2±0.1 g/cm3 Boiling Point 407.0±38.0 °C at 760 mmHg
Molecular Formula C16H6D8O4 Melting Point N/A
MSDS N/A Flash Point 204.7±25.2 °C

 Use of Dimethyl biphenyl-4,4'-dicarboxylate-d8


Dimethyl biphenyl-4,4'-dicarboxylate-d8 is the deuterium labeled Dimethyl biphenyl-4,4'-dicarboxylate[1]. Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a hepatoprotectant obtained from Schizandra fructus and may induce a signal transduction similar to that associated with IFN[2].

 Names

Name Dimethyl 4,4'-(2H8)biphenyldicarboxylate
Synonym More Synonyms

 Dimethyl biphenyl-4,4'-dicarboxylate-d8 Biological Activity

Description Dimethyl biphenyl-4,4'-dicarboxylate-d8 is the deuterium labeled Dimethyl biphenyl-4,4'-dicarboxylate[1]. Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a hepatoprotectant obtained from Schizandra fructus and may induce a signal transduction similar to that associated with IFN[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Joo SS, et al. Interferon signal transduction of biphenyl dimethyl dicarboxylate/amantadine and anti-HBV activity in HepG2 2.2.15. Arch Pharm Res. 2006 May;29(5):405-11.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 407.0±38.0 °C at 760 mmHg
Molecular Formula C16H6D8O4
Molecular Weight 278.329
Flash Point 204.7±25.2 °C
Exact Mass 278.139435
LogP 3.71
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.559

 Synonyms

[1,1'-Biphenyl-d]-4,4'-dicarboxylic acid, dimethyl ester
Dimethyl 4,4'-(H)biphenyldicarboxylate
Dimethyl (H)biphenyl-4,4'-dicarboxylate