1219798-52-3

1219798-52-3 structure

Name: Terbuthylazine-desethyl-d9
Chemical Name: 6-Chloro-N-[2-(2H3)methyl(2H6)-2-propanyl]-1,3,5-triazine-2,4-diamine
CAS Number: 1219798-52-3
Molecular Formula: C₇H₃D₉ClN₅
Molecular Weight: 210.712
Catalog: Research Areas Others
Create Date: 2018-05-12 12:27:05
Modify Date: 2024-01-02 11:47:17
Terbuthylazine-desethyl-d9 is the deuterium labeled Terbuthylazine-desethyl[1]. Terbuthylazine-desethyl (Desethylterbuthylazine) is a chloro dealkylated metabolite of Terbuthylazine (a triazine herbicide)[2][3].

Name	6-Chloro-N-[2-(2H3)methyl(2H6)-2-propanyl]-1,3,5-triazine-2,4-diamine
Synonyms	6-Chloro-N-[2-(H)methyl(H)-2-propanyl]-1,3,5-triazine-2,4-diamine 1,3,5-Triazine-2,4-diamine, 6-chloro-N-[1,1-di(methyl-d)ethyl-2,2,2-d]- 6-Chloro-N-[2-(H)methyl(H)propan-2-yl]-1,3,5-triazine-2,4-diamine

Description	Terbuthylazine-desethyl-d9 is the deuterium labeled Terbuthylazine-desethyl[1]. Terbuthylazine-desethyl (Desethylterbuthylazine) is a chloro dealkylated metabolite of Terbuthylazine (a triazine herbicide)[2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Potter TL, et, al. Tillage, cover-crop residue management, and irrigation incorporation impact on fomesafen runoff. J Agric Food Chem. 2011 Jul 27;59(14):7910-5. [3]. Navarro S, et, al. Determination of simazine, terbuthylazine, and their dealkylated chlorotriazine metabolites in soil using sonication microextraction and gas chromatography. J AOAC Int. Sep-Oct 200083(5):1239-43.