Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Alstonine
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Huang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Alstonine
Price: ￥4118.0/5mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Alstonine
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

642-18-2

642-18-2 structure

642-18-2 structure

Name: Alstonine
Chemical Name: Propoxybenzene
CAS Number: 642-18-2
Molecular Formula: C₂₁H₂₀N₂O₃
Molecular Weight: 348.41
Catalog: Natural product Alkaloid
Create Date: 2018-05-01 03:47:50
Modify Date: 2024-01-08 13:34:28
Alstonine is a major indole alkaloid compound of a plant-based remedy. Alstonine has antipsychotic, anxiolytic, anticancer and antimalarial properties[1].

Name	Propoxybenzene
Synonyms	Benzene, propoxy- phenylether Propoxybenzene PHENYL PROPYL ETHER Alstonine

Description	Alstonine is a major indole alkaloid compound of a plant-based remedy. Alstonine has antipsychotic, anxiolytic, anticancer and antimalarial properties[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Research Areas >> Neurological Disease
In Vitro	Alstonine has the capacity to distinguish cancer DNA from healthy tissue DNA; it inhibits DNA in vitro synthesis when DNA from different cancerous tissues or cells is used as template. Practically without effects on DNA from healthy tissues[1].
In Vivo	In mice models Alstonine shows a clear, dose-dependent, potent antipsychotic profile. Alstonine (i.p.) prevents amphetamine-induced lethality, with active doses within the range of 0.5-2.0 mg/kg[1]. Alstonine (0.1, 0.5 and 1.0 mg/kg) prevents MK-801 induced hyperlocomotion. Because Alstonine partially reverses MK-801-induced increase in locomotion both at the hole-board and locomotor activity cages[1]. Alstonine successfully treats a relatively important proportion of BALB/C mice inoculated with transplantable YC8 lymphoma ascites cells as well as Swiss mice bearing Ehrlich ascites carcinoma cells[1].
References	[1]. E Elisabetsky, et al. The Alkaloid Alstonine: A Review of Its Pharmacological Properties. Evid Based Complement Alternat Med. 2006 Mar;3(1):39-48.

Density	0.9±0.1 g/cm3
Boiling Point	189.9±0.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₀N₂O₃
Molecular Weight	348.41
Flash Point	65.0±8.0 °C
LogP	3.20
Vapour Pressure	0.8±0.3 mmHg at 25°C
Index of Refraction	1.488

Hazard Codes	Xi