11113-62-5

11113-62-5 structure

Name: Enniatin complex
Chemical Name: (3S,6R,9S,12R,15S,18R)-3,6,9,12,15,18-hexaisopropyl-4,10,16-trimethyl-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;(3S,6R,9S,12R,15S,18R)-3,6,9,12,18-pentaisopropyl-4,10,16-trimethyl-15-[(1S)-1-methylpropyl]-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;(3S,6R,9S,12R,15S,18S)-3,6,12,18-tetraisopropyl-4,10,16-trimethyl-9,15-bis[(1S)-1-methylpropyl]-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;(3S,6R,9S,12R,15S,18R)-6,12,18-triisopropyl-4,10,16-trimethyl-3,9,15-tris[(1S)-1-methylpropyl]-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone
CAS Number: 11113-62-5
Molecular Formula: C₁₃₈H₂₄₀N₁₂O₃₆
Molecular Weight: 2643.441
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-02-14 09:31:32
Modify Date: 2024-02-08 08:42:49
Enniatin complex is a mixture of cyclohexadepsipeptides isolated largely from Fusarium species of fungi, and has ionophoric, antibiotic, and in vitro hypolipidaemic properties. Enniatin complex inhibits enzymes like acyl-CoA: cholesterol acyl transferase and induces apoptosis in several cancer lines [1][2].

Name	(3S,6R,9S,12R,15S,18R)-3,6,9,12,15,18-hexaisopropyl-4,10,16-trimethyl-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;(3S,6R,9S,12R,15S,18R)-3,6,9,12,18-pentaisopropyl-4,10,16-trimethyl-15-[(1S)-1-methylpropyl]-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;(3S,6R,9S,12R,15S,18S)-3,6,12,18-tetraisopropyl-4,10,16-trimethyl-9,15-bis[(1S)-1-methylpropyl]-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;(3S,6R,9S,12R,15S,18R)-6,12,18-triisopropyl-4,10,16-trimethyl-3,9,15-tris[(1S)-1-methylpropyl]-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone

Description	Enniatin complex is a mixture of cyclohexadepsipeptides isolated largely from Fusarium species of fungi, and has ionophoric, antibiotic, and in vitro hypolipidaemic properties. Enniatin complex inhibits enzymes like acyl-CoA: cholesterol acyl transferase and induces apoptosis in several cancer lines [1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Kamyar M, et al. Investigation of the electrophysiological properties of enniatins. Arch Biochem Biophys. 2004 Sep 15;429(2):215-23. [2]. Dornetshuber R, et al. Enniatin exerts p53-dependent cytostatic and p53-independent cytotoxic activities against humancancer cells. Chem Res Toxicol. 2007 Mar;20(3):465-73.