2503-13-1
2503-13-1 structure
- Name: Enniatin A
- Chemical Name: enniatin A
- CAS Number: 2503-13-1
- Molecular Formula: C36H63N3O9
- Molecular Weight: 681.90000
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Acyltransferase
- Create Date: 2017-05-23 20:07:01
- Modify Date: 2026-08-06 17:58:12
-
Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 22 μM in an enzyme assay using rat liver microsomes[1].
| Name | enniatin A |
|---|---|
| Synonyms |
Cyclo[(2R)- 2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl- N-methyl-L- isoleucyl]
ENNIATIN A (3S,6R,9S,12R,15S,18R)-3,9,15-tris[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,18-tri(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone Lateritin I Enniatin-A N-Methylcyclo(L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-) ENNIATIN A (LATERITIN I) |
| Description | Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 22 μM in an enzyme assay using rat liver microsomes[1]. |
|---|---|
| Related Catalog | |
| Target |
ACAT |
| In Vitro | Enniatin A exhibits cytotoxic effects in HeLa cell lines with IC50s of 1.15 μM concentration for 24 h and 0.57 μM concentration for 48 h[2]. |
| References |
| Density | 1.022±0.06 g/cm3 |
|---|---|
| Boiling Point | 847.4±65.0 °C |
| Melting Point | 122-124 °C |
| Molecular Formula | C36H63N3O9 |
| Molecular Weight | 681.90000 |
| Exact Mass | 681.45600 |
| PSA | 139.83000 |
| LogP | 4.13640 |
| Vapour Pressure | 5.53E-29mmHg at 25°C |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H311-H331 |
| Precautionary Statements | P261-P280-P301 + P310-P311 |
| Hazard Codes | T |
| Risk Phrases | 23/24/25 |
| RIDADR | UN 2811 |
| Precursor 0 | |
|---|---|
| DownStream 2 | |
