191102-87-1
191102-87-1 structure
- Name: GGTI-2147
- Chemical Name: Methyl N-{4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthyl)benzoyl}-L-leucinate
- CAS Number: 191102-87-1
- Molecular Formula: C28H30N4O3
- Molecular Weight: 470.563
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ROS
- Create Date: 2018-03-02 14:29:04
- Modify Date: 2024-02-04 10:35:24
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GGTI-2147 is a potent GGTase I inhibitor. GGTI-2147 blocks geranyl-geranylation of Rap1A and reduces the activity of Rac1 (one of substrates for GGTI) and ameliorates the OGD/R-induced neuronal apoptosis.GGTI-2147 can be used for neurodevelopmental disorders research, such as autism, depression, and schizophrenia[1].
| Name | Methyl N-{4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthyl)benzoyl}-L-leucinate |
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| Synonyms |
Methyl N-{4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthyl)benzoyl}-L-leucinate
methyl N-{4-[(1H-imidazol-4-ylmethyl)amino]-2-(naphthalen-1-yl)benzoyl}-L-leucinate L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester |
| Description | GGTI-2147 is a potent GGTase I inhibitor. GGTI-2147 blocks geranyl-geranylation of Rap1A and reduces the activity of Rac1 (one of substrates for GGTI) and ameliorates the OGD/R-induced neuronal apoptosis.GGTI-2147 can be used for neurodevelopmental disorders research, such as autism, depression, and schizophrenia[1]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 710.6±60.0 °C at 760 mmHg |
| Molecular Formula | C28H30N4O3 |
| Molecular Weight | 470.563 |
| Flash Point | 383.5±32.9 °C |
| Exact Mass | 470.231781 |
| LogP | 4.23 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.640 |