GGTI-2147
Modify Date: 2024-02-04 10:35:24
GGTI-2147 structure
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Common Name | GGTI-2147 | ||
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| CAS Number | 191102-87-1 | Molecular Weight | 470.563 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 710.6±60.0 °C at 760 mmHg | |
| Molecular Formula | C28H30N4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 383.5±32.9 °C | |
Use of GGTI-2147GGTI-2147 is a potent GGTase I inhibitor. GGTI-2147 blocks geranyl-geranylation of Rap1A and reduces the activity of Rac1 (one of substrates for GGTI) and ameliorates the OGD/R-induced neuronal apoptosis.GGTI-2147 can be used for neurodevelopmental disorders research, such as autism, depression, and schizophrenia[1]. |
| Name | Methyl N-{4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthyl)benzoyl}-L-leucinate |
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| Synonym | More Synonyms |
| Description | GGTI-2147 is a potent GGTase I inhibitor. GGTI-2147 blocks geranyl-geranylation of Rap1A and reduces the activity of Rac1 (one of substrates for GGTI) and ameliorates the OGD/R-induced neuronal apoptosis.GGTI-2147 can be used for neurodevelopmental disorders research, such as autism, depression, and schizophrenia[1]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 710.6±60.0 °C at 760 mmHg |
| Molecular Formula | C28H30N4O3 |
| Molecular Weight | 470.563 |
| Flash Point | 383.5±32.9 °C |
| Exact Mass | 470.231781 |
| LogP | 4.23 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.640 |
| Methyl N-{4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthyl)benzoyl}-L-leucinate |
| methyl N-{4-[(1H-imidazol-4-ylmethyl)amino]-2-(naphthalen-1-yl)benzoyl}-L-leucinate |
| L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester |