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80506-64-5

80506-64-5 structure
80506-64-5 structure
  • Name: Methoxypolyethylene glycol amine
  • Chemical Name: Methoxypolyethylene glycol amine
  • CAS Number: 80506-64-5
  • Molecular Formula: (C2H4O)nC3H9NO
  • Molecular Weight: 3400(Average)
  • Catalog: Catalysts and additives Polyethylene glycol derivative
  • Create Date: 2018-07-21 18:20:12
  • Modify Date: 2024-01-05 12:24:32
  • mPEG-amine (MW 3400) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

Name Methoxypolyethylene glycol amine
Synonyms MFCD00131599
Methoxypoly(ethylene glycol) aMine
mPEG-NH2
MPEG12-amine
MPEG12-NH2
2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontan-37-amine
m-PEG12-amine
α-methoxy-ω-amino poly (ethylene glycol)
Description mPEG-amine (MW 3400) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
Related Catalog
References

[1]. Han X, et al. 9-NC-loaded folate-conjugated polymer micelles as tumor targeted drug delivery system: preparation and evaluation in vitro. Int J Pharm. 2009 May 8;372(1-2):125-31.  

Density 1.1±0.1 g/cm3
Boiling Point 583.6±45.0 °C at 760 mmHg
Melting Point 58-61 °C(lit.)
Molecular Formula (C2H4O)nC3H9NO
Molecular Weight 3400(Average)
Flash Point 291.3±22.4 °C
Exact Mass 559.357
LogP -4.59
Appearance Granular Solid
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.458
Storage condition −20°C
Water Solubility Soluble in water
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes C
Safety Phrases S22;S24/25
RIDADR NONH for all modes of transport
WGK Germany 3