1005264-47-0
1005264-47-0 structure
- Name: MX69
- Chemical Name: MX69
- CAS Number: 1005264-47-0
- Molecular Formula: C27H26N2O4S
- Molecular Weight: 474.5794
- Catalog: Signaling Pathways Apoptosis IAP
- Create Date: 2018-06-29 21:45:59
- Modify Date: 2025-08-23 13:02:14
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MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment.
| Name | MX69 |
|---|
| Description | MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment. |
|---|---|
| Related Catalog | |
| In Vitro | MX69 blocks the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation. MX69 shows minimal inhibitory effect on normal human hematopoiesis in vitro and is very well tolerated in animal models. MX69-induced MDM2 downregulation results not only in inhibition of XIAP expression, but also in activation of p53, which contributes to cancer cell apoptosis in vitro[1]. |
| In Vivo | MX69-induced MDM2 downregulation results in activation of p53 which contributes to inhibition of cancer cell proliferation in vivo[1]. |
| References |
| Molecular Formula | C27H26N2O4S |
|---|---|
| Molecular Weight | 474.5794 |
| Storage condition | -20℃ |