183598-56-3

183598-56-3 structure
183598-56-3 structure
  • Name: Leptin (22-56) (human)
  • Chemical Name: Leptin (22-56) (human)
  • CAS Number: 183598-56-3
  • Molecular Formula: C171H298N50O56
  • Molecular Weight: 3950.52
  • Catalog: Peptides
  • Create Date: 2018-05-20 08:00:00
  • Modify Date: 2024-01-06 21:52:38
  • Leptin (22-56), human is the fragment of leptin, mediated via several isoforms of receptors (Ob-Rs).

Name Leptin (22-56) (human)
Synonyms Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys
Description Leptin (22-56), human is the fragment of leptin, mediated via several isoforms of receptors (Ob-Rs).
Related Catalog
Target

Ob-Rs[1]

In Vitro Leptin (22-56), human is the fragment of leptin, inhibits corticosterone production, but shows no effect on the proliferation of cultured adrenocortical cells. Leptin (22-56) may be responsible for the direct inhibitory effect on secretion and growth of leptin on cultured rat adrenocortical cells[1]. Leptin (22-56) inhibits food intake, and may favour erythropoiesis[2].
References

[1]. Malendowicz LK, et al. Effects of leptin and leptin fragments on corticosterone secretion and growth of cultured rat adrenocortical cells. Int J Mol Med. 2004 Nov;14(5):873-7.

[2]. Stamatiadis DN, et al. Elevated leptin fragments in renal failure correlate with BMI and haematopoiesis and are normalized by haemodialysis. Clin Endocrinol (Oxf). 2004 Apr;60(4):434-41.

Molecular Formula C171H298N50O56
Molecular Weight 3950.52