Leptin (22-56) (human)

Modify Date: 2024-01-06 21:52:38

Leptin (22-56) (human) Structure
Leptin (22-56) (human) structure
Common Name Leptin (22-56) (human)
CAS Number 183598-56-3 Molecular Weight 3950.52
Density N/A Boiling Point N/A
Molecular Formula C171H298N50O56 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Leptin (22-56) (human)


Leptin (22-56), human is the fragment of leptin, mediated via several isoforms of receptors (Ob-Rs).

 Names

Name Leptin (22-56) (human)
Synonym More Synonyms

 Leptin (22-56) (human) Biological Activity

Description Leptin (22-56), human is the fragment of leptin, mediated via several isoforms of receptors (Ob-Rs).
Related Catalog
Target

Ob-Rs[1]

In Vitro Leptin (22-56), human is the fragment of leptin, inhibits corticosterone production, but shows no effect on the proliferation of cultured adrenocortical cells. Leptin (22-56) may be responsible for the direct inhibitory effect on secretion and growth of leptin on cultured rat adrenocortical cells[1]. Leptin (22-56) inhibits food intake, and may favour erythropoiesis[2].
References

[1]. Malendowicz LK, et al. Effects of leptin and leptin fragments on corticosterone secretion and growth of cultured rat adrenocortical cells. Int J Mol Med. 2004 Nov;14(5):873-7.

[2]. Stamatiadis DN, et al. Elevated leptin fragments in renal failure correlate with BMI and haematopoiesis and are normalized by haemodialysis. Clin Endocrinol (Oxf). 2004 Apr;60(4):434-41.

 Chemical & Physical Properties

Molecular Formula C171H298N50O56
Molecular Weight 3950.52

 Synonyms

Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys