1923833-60-6

1923833-60-6 structure

Name: Linrodostat (BMS-986205)
Chemical Name: BMS-986205
CAS Number: 1923833-60-6
Molecular Formula: C₂₄H₂₄ClFN₂O
Molecular Weight: 410.15
Catalog: Signaling Pathways Metabolic Enzyme/Protease Indoleamine 2,3-Dioxygenase (IDO)
Create Date: 2018-06-22 01:11:09
Modify Date: 2024-01-08 08:36:46
BMS-986205 is a selective indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.

Name	BMS-986205

Description	BMS-986205 is a selective indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO) Research Areas >> Cancer
Target	IDO1
References	[1]. Lillian L. Siu, et al. Abstract CT116: BMS-986205, an optimized indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor, is well tolerated with potent pharmacodynamic (PD) activity, alone and in combination with nivolumab (nivo) in advanced cancers in a phase 1/2a trial. AACR; Cancer Res. 2017; 77 (13 Suppl): Abstract nr CT116.