1402837-77-7
1402837-77-7 structure
- Name: IDO-IN-8
- Chemical Name: IDO-IN-8
- CAS Number: 1402837-77-7
- Molecular Formula: C18H21FN2O2
- Molecular Weight: 316.370
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Indoleamine 2,3-Dioxygenase (IDO)
- Create Date: 2018-01-11 13:47:48
- Modify Date: 2024-01-24 19:53:50
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IDO-IN-8 (NLG-1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1487, has an IC50 of 1-10 μM.
| Name | IDO-IN-8 |
|---|---|
| Synonyms |
5H-Imidazo[5,1-a]isoindole-5-ethanol, 6-fluoro-α-(trans-4-hydroxycyclohexyl)-, (αS,5R)-
trans-4-{(1S)-2-[(5R)-6-Fluoro-5H-imidazo[5,1-a]isoindol-5-yl]-1-hydroxyethyl}cyclohexanol |
| Description | IDO-IN-8 (NLG-1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1487, has an IC50 of 1-10 μM. |
|---|---|
| Related Catalog | |
| Target |
IDO:1-10 μM (IC50) |
| In Vitro | IDO-IN-8 (Compound 1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 1-10 μM (this is the concentration of IDO-IN-8 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 555.4±35.0 °C at 760 mmHg |
| Molecular Formula | C18H21FN2O2 |
| Molecular Weight | 316.370 |
| Flash Point | 289.7±25.9 °C |
| Exact Mass | 316.158691 |
| LogP | 1.28 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.683 |
| Storage condition | 2-8℃ |