713492-66-1
713492-66-1 structure
- Name: Mcl1-IN-1
- Chemical Name: Mcl1-IN-1
- CAS Number: 713492-66-1
- Molecular Formula: C23H18ClN3O4
- Molecular Weight: 435.860
- Catalog: Signaling Pathways Apoptosis Bcl-2 Family
- Create Date: 2018-05-26 12:03:35
- Modify Date: 2024-01-02 11:07:57
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Mcl1-IN-1 is an inhibitor of myeloid cell factor 1 (Mcl-1) (IC50=2.4 µM).
| Name | Mcl1-IN-1 |
|---|---|
| Synonyms |
{2-[(5-Chloro-8-hydroxy-7-quinolinyl)(2-pyridinylamino)methyl]phenoxy}acetic acid
Acetic acid, 2-[2-[(5-chloro-8-hydroxy-7-quinolinyl)(2-pyridinylamino)methyl]phenoxy]- |
| Description | Mcl1-IN-1 is an inhibitor of myeloid cell factor 1 (Mcl-1) (IC50=2.4 µM). |
|---|---|
| Related Catalog | |
| Target |
Mcl-1:2.4 μM (IC50) |
| In Vitro | Mcl1-IN-1 (Compound 1) is a Mcl-1 inhibitor, which demonstrates good Mcl-1 inhibition (IC50=2.4 µM) with no appreciable inhibition of Bcl-xL at 100 µM[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 681.6±55.0 °C at 760 mmHg |
| Molecular Formula | C23H18ClN3O4 |
| Molecular Weight | 435.860 |
| Flash Point | 366.0±31.5 °C |
| Exact Mass | 435.098572 |
| LogP | 4.02 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.721 |
| Storage condition | 2-8℃ |