Mcl1-IN-1

Modify Date: 2024-01-02 11:07:57

Mcl1-IN-1 Structure
Mcl1-IN-1 structure
Common Name Mcl1-IN-1
CAS Number 713492-66-1 Molecular Weight 435.860
Density 1.5±0.1 g/cm3 Boiling Point 681.6±55.0 °C at 760 mmHg
Molecular Formula C23H18ClN3O4 Melting Point N/A
MSDS N/A Flash Point 366.0±31.5 °C

 Use of Mcl1-IN-1


Mcl1-IN-1 is an inhibitor of myeloid cell factor 1 (Mcl-1) (IC50=2.4 µM).

 Names

Name Mcl1-IN-1
Synonym More Synonyms

 Mcl1-IN-1 Biological Activity

Description Mcl1-IN-1 is an inhibitor of myeloid cell factor 1 (Mcl-1) (IC50=2.4 µM).
Related Catalog
Target

Mcl-1:2.4 μM (IC50)

In Vitro Mcl1-IN-1 (Compound 1) is a Mcl-1 inhibitor, which demonstrates good Mcl-1 inhibition (IC50=2.4 µM) with no appreciable inhibition of Bcl-xL at 100 µM[1].
References

[1]. Richard DJ, et al. Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker. Bioorg Med Chem. 2013 Nov 1;21(21):6642-9.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 681.6±55.0 °C at 760 mmHg
Molecular Formula C23H18ClN3O4
Molecular Weight 435.860
Flash Point 366.0±31.5 °C
Exact Mass 435.098572
LogP 4.02
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.721
Storage condition 2-8℃

 Synonyms

{2-[(5-Chloro-8-hydroxy-7-quinolinyl)(2-pyridinylamino)methyl]phenoxy}acetic acid
Acetic acid, 2-[2-[(5-chloro-8-hydroxy-7-quinolinyl)(2-pyridinylamino)methyl]phenoxy]-
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Price: $462/10mM*1mLinDMSO

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